The use of T-cells to fight cancer

Dr. Miguel Reina-Campos is an Assistant Professor at the La Jolla Institute for Immunology, where he leads the Laboratory of Tissue Immune Networks. A biochemist from Barcelona with expertise in cancer cell biology and immunology, his research centers on tissue-resident CD8⁺ T cells: specialized immune sentinels embedded in organs such as the liver and colon. By uncovering how these “professional survivalists” adapt to different tissue environments, his lab aims to harness their strategies to strengthen cancer immunotherapies and potentially address autoimmune diseases. Using advanced tools like spatial transcriptomics and CRISPR, Dr. Reina-Campos seeks to reveal the hidden lives of immune cells and collaborate across disciplines to accelerate life-saving treatments.